Allergy, Arthritis and Immunology Testing
Creative Diagnostics Recombinant Human Tryptase beta-2 Protein
Human β tryptase enzymes have been cloned and stably expressed in Pichia pastoris as fully active tetrameric enzymes and purified by affinity chromatography. rhLung Tryptase is provided at a high concentration (2mg/ml) in minimal buffer without heparin for chromatographic studies and with glycosylation more closely resembling cadaveric enzyme as demonstrated by glycosidase digestion followed by Western analysis of the recombinant enzyme and native lung tryptase.
Cayman Chemical Rheum hotaoense AstrngIn 1mg
A dual inhibitor of Mps1/TTK and Clk2 (IC50s 5 and 3 nM respectively) selective for Mps1/TTK and Clk2 over a panel of 255 kinases at 3 M inhibit DYRK3 DYRK1A PHKG DYRK1B and Clk1 (IC50s 99 104 136 157 and 300 nM respectively) selectively inhibits the growth of Cal-51 TNBC cell over BT-474 luminal breast cancer cells (IC50s 60 and 6970 nM respectively) reduces tumor volume in a Cal-51 mouse xenograft model at 20 mg/kg
Cayman Chemical ApIum graveolens ApIIn 10mg
An alkaloid with diverse biological activities inhibits 5-HT reuptake by OCT2 and dopamine reuptake by OCT3 (IC50s 0.137 and 0.354 UM respectively for human recombinant transporters) as well as reduces dopamine 5-HT and norepinephrine reuptake in mouse brain synaptosomes decreases immobility time in the forced swim test in a mouse model of depression induced by chronic unpredictable mild stress at 1.5 and 3 mg/kg reduces acetic acid-induced writhing in mice and increases the mechanical paw withdrawal threshold in a mouse model of bone cancer pain at 10 mg/kg
Cayman Chemical PAMAM Dendrimer G4 5 Carboxyl
A metabolite of cyclobenzaprine a potential impurity in commercial preparations of cyclobenzaprine
Cayman Chemical PAMAM DendrImR G4 5 Carboxyl
A STAT3 inhibitor (Ki 10.46 UM) selective for STAT3 over STAT1 (Ki 100 UM) prevents constitutively active STAT3 DNA binding in NIH3T3 fibroblast nuclear extracts (IC50 3.9 UM) cytotoxic to AR230 and imatinib-resistant AR230 cells (IC50s 8.1 and 7 UM respectively) and a variety of glioblastoma CSCs (IC50s 0.195-1.12 UM) reduces tumor growth in MDA-MB-231 breast cancer and U-251MG glioblastoma mouse xenograft models at 3 and 5 mg/kg respectively active against T. gondii at 5 UM
Cayman Chemical PAMAM DendrImR G4 0 AmIdoeth
An inhibitor of SUMO-activating enzyme (IC50s 0.003 and 0.011 UM with SUMO1 or SUMO2 respectively as the ubiquitin-like proteins) selective for SAE over NAE and UAE (IC50s 32 and 100 UM respectively) decreases global SUMOylation in HCT116 cells (EC50 0.019 UM) as well as decreases the viability of MDA-MB-468 and A375 cells (EC50s 0.06 and 0.45 UM respectively) reduces tumor growth in an HCT116 mouse xenograft model at 150 and 200 mg/kg twice per day
Cayman Chemical Rheum hotaoense Astrngn 10mg
A dual inhibitor of Mps1/TTK and Clk2 (IC50s 5 and 3 nM respectively) selective for Mps1/TTK and Clk2 over a panel of 255 kinases at 3 M inhibit DYRK3 DYRK1A PHKG DYRK1B and Clk1 (IC50s 99 104 136 157 and 300 nM respectively) selectively inhibits the growth of Cal-51 TNBC cell over BT-474 luminal breast cancer cells (IC50s 60 and 6970 nM respectively) reduces tumor volume in a Cal-51 mouse xenograft model at 20 mg/kg
Cayman Chemical PAMAM Dendrimer G4 0 Succinam
An a2-AR agonist epidural administration induces antinociception and sedation in donkeys at 50 Ug/kg induces bradycardia in horses from 0.04-0.12 mg/kg
Seracare Life Sciences Inc 5X DETECTOR BLOCK
Detector Block is recommended as a general blocking agent for use in membrane-based detection assays. It is especially useful when traditional blocking solutions (I.e., milk, BSA, casein) reduce sensitivity or do not adequately block background. Detector Block can be used as both a blocking solution and a conjugate diluent in membrane applications such as Western, Northern, and Southern blotting.
Seracare Life Sciences Inc VIBRIO SPECIES POS CTRL
Heat-killed Vibrio cholerae, Vibro parahaemolyticus, and Vibrio vulnificus cells in dextran solution. Lot specific cell counts can be obtained by requesting a Certificate of Analysis or by calling Technical Services with the specific lot number.
Seracare Life Sciences Inc E COLI O26:H11 SPECIES POS CON
Heat-killed Escherichia coli O26:H11 cells in dextran solution. It is intended for use as a positive control in immunoassays designed for E.coli O26 detection.
BD Cell Analysis 3P BDTM STEM CELL CTRL KT
Product shelf life is 6 weeks. Confirm product expiry date when ordering. Stem Cell Control Kit (Bi-Level Control). 1 x 2.0 ml CD34+ Low approx. 10 cells/ul, and 1 x 2.0 ml CD34+ High approx. 35 cells/ul.
Sigma Aldrich Fine Chemicals Biosciences Whey bovine milk spra2.5KG
Whey proteins isolated from bovine milk plays a vital role in regulating immune responses. -lactoglobulin is one of the highly expressed proteins in the bovine whey.